Concept of BuBc in neonatal jaundice – needs a change

Kalpana Singh, Auxilia Borrison, Abbas Ali Mahdi
4.268 1.334


Orthoclinical diagnostics Vitros microslide came with a method by which Bu and Bc can be estimated directly. The advantage of this microslide technology is that conjugated bilirubin (Bc) does not contain delta bilirubin and the fractions i.e BuBc are actually estimated. TBil estimation is also available based on traditional diazo method on the same instrument


conjugated bilirubin, neonatal jaundice, photobilirubin, unconjugated bilirubin

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Porten ML,

Hyperbilirubinemia in the term newborn. Am Fam Physician 2002; 65: 599 – 606. 2. Dennis

BL. Doumas BT, Wu TW. The measurement of bilirubin fractions of serum. Crit Rev Clin Lab Sci 1991; 28: 415 – 445.

Harb R, Thomas DW. Conjugated hyperbilirubinemia: screening and treatment in older infants and children. Pediatric in Review 2007; 28: 83 – 91.

Davis AR, Rosenthal P, Escobar GJ, Newman TB. Interpreting conjugated bilirubin levels in newborns. J Pediatr 2011; 158: 562 – 565.