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Hematopoetic stem cell transplantation in children

M Akif YESILIPEK, Gulsun KARASU
2.751 923

Abstract


Hematopoietic stem cell transplantation (HSCT) has been an established as a curative therapy for the various hematologic nonmalignant and malignant diseases in childhood. In addition to conventional indications like hematological malignancies, aplastic anemia and solid tumours, a gerat deal of inborn errors in children can be cured with HSCT. Recent applications and recommendations in terms of stem cell sources, indications, conditioning and post-transplant complications in children like infectious complications, graft versus host disease (GVHD), gastrointestinal and liver complications, pulmonary complications and late endocrine effects are discussed in this review.

Keywords


hematopoietic stem cell transplantation, children, stem cell source, indications, complications, supportive therapy, late effects

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